NAD+ 250mg Buffered
What does "Coenzyme/Anti-Aging" mean?
A moderate-dose, pH-stabilized form of NAD+. The 250mg concentration offers a balance between efficacy and tolerability for research applications.
Explained Simply
This is a medium-sized dose of the cell-powering molecule NAD+. The buffering makes it gentler, like diluting medicine to make it easier to take.
How It Works
Same mechanism as standard NAD+ - participates in cellular energy production and serves as a substrate for longevity-associated enzymes. The 250mg dose provides meaningful NAD+ supplementation.
Research by Sex
Effects in Men
- •Moderate dosing may suit initial research protocols
- •NAD+ benefits observed at this concentration
- •Allows for gradual dose escalation studies
Effects in Women
- •Well-tolerated in female subjects
- •Research shows consistent NAD+ elevation
- •Metabolic benefits observed at this dose level
Key Terms Explained
Dose titration
Gradually adjusting the dose to find the optimal amount
Bioavailability
The proportion of a substance that enters circulation and has an active effect
Research Areas
- •Dose-finding studies
- •NAD+ kinetics and metabolism
- •Comparative bioavailability research
- •Tolerability optimization
Published Studies
Laboratory Protocols
Storage
Store at -20°C protected from light and moisture.
Reconstitution
Follow manufacturer instructions for buffered formulation.
Quick Facts
Category
Coenzyme/Anti-Aging
Molecular Weight
663.43 g/mol
Half-Life
~2-4 hours
Amino Acid Sequence
N/A (Small molecule coenzyme, not a peptide)
Research Grade NAD+ 250mg Buffered
Browse our selection of NAD+ 250mg Buffered from verified vendors.
View ProductsGrokipedia
Quick Reference
View detailed research data including key facts, mechanism of action, and safety profile.
Disclaimer: This information is provided for educational purposes only. These products are intended for laboratory research use only. Not for human consumption.
Grokipedia
Quick Reference
NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is a dinucleotide coenzyme essential for cellular energy metabolism. It serves dual functions as a coenzyme in redox reactions and as a substrate for NAD+-consuming enzymes including sirtuins and PARPs.
Key Facts
- •Molecular weight: 663.43 g/mol
- •Essential coenzyme in all cells
- •Declines significantly with age
- •Required for 500+ enzymatic reactions
- •Sirtuin and PARP substrate
Mechanism of Action
Shuttles electrons in redox reactions for ATP production. Serves as fuel for sirtuins (longevity proteins) and PARPs (DNA repair). Levels decline ~50% between ages 40-60, correlating with aging phenotypes.
Research Applications
- Cellular energy metabolism research
- Longevity and aging studies
- DNA repair mechanism research
- Neuroprotection studies
Safety Profile
Essential endogenous molecule. Supplementation generally well-tolerated. IV administration may cause flushing. Buffered formulations improve tolerability.
Disclaimer: This information is for educational and research purposes only. Products are intended for laboratory research use only. Not for human consumption.