TB4 (Thymosin Beta-4 Full Sequence)
What does "Healing/Recovery Peptide" mean?
TB4 refers to the complete Thymosin Beta-4 protein. This 43-amino acid peptide is found naturally in almost every cell type and plays a crucial role in tissue development and repair.
Explained Simply
TB4 is like a master organizer for your cells. It helps control the tiny ropes and structures inside cells that let them move, divide, and heal. Think of it as a construction foreman for cellular repair projects.
How It Works
TB4 binds to monomeric G-actin in a 1:1 complex, preventing spontaneous polymerization. This dynamic regulation is essential for controlled cell migration, tissue repair, and wound healing processes.
Research by Sex
Effects in Men
- •Research demonstrates consistent tissue regeneration in male subjects
- •Studies on cardiac repair show promising results in male models
- •Skeletal muscle recovery research includes male populations
Effects in Women
- •Wound healing mechanisms function identically in female subjects
- •Research on dermal repair shows consistent outcomes
- •Anti-inflammatory benefits observed across both sexes
Key Terms Explained
G-actin
Globular actin, the monomeric form of actin that can polymerize into filaments
Actin sequestering
The process of binding and storing actin monomers to control when and where they form structures
Research Areas
- •Actin dynamics and cell motility
- •Cardiac regeneration after injury
- •Corneal wound healing
- •Dermal wound repair
- •Anti-fibrotic effects
Published Studies
Laboratory Protocols
Storage
Store lyophilized peptide at -20°C protected from moisture.
Reconstitution
Reconstitute with sterile water or bacteriostatic water. Swirl gently until dissolved.
Quick Facts
Category
Healing/Recovery Peptide
Molecular Weight
4963.44 g/mol
Half-Life
~2-4 hours
Amino Acid Sequence
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Research Grade TB4 (Thymosin Beta-4 Full Sequence)
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Quick Reference
TB-500 (Thymosin Beta-4)
TB-500 is a synthetic version of the active region of Thymosin Beta-4, a 43-amino acid peptide found in almost all human and animal cells. It regulates actin, a protein essential for cell structure and movement.
Key Facts
- •43-amino acid peptide
- •Molecular weight: 4963.44 g/mol
- •Half-life: 2-4 hours
- •Actin-sequestering protein
- •Found in nearly all cell types
Mechanism of Action
Sequesters G-actin monomers, regulating actin polymerization critical for cell motility. Controls how cells move, divide, and heal. Influences wound healing, cardiac tissue repair, and inflammatory responses.
Research Applications
- Wound healing and tissue repair
- Cardiac regeneration research
- Hair follicle studies
- Anti-inflammatory research
Safety Profile
Research compound. Well-characterized mechanism. Animal studies show tissue repair benefits. Human clinical data limited. Research use only.
Disclaimer: This information is for educational and research purposes only. Products are intended for laboratory research use only. Not for human consumption.